Helfrich-Förster C, Domenie ED, Mitesser O, Hovestadt T, Ferlin A, Wehr TA, Costa R, Montagnese S Sci Adv To increase reproductive success, many species synchronize reproductive behavior with a particular phase of the lunar cycle. The human menstrual cycle has also a period close to that of the lunar cycle, and recent studies suggest a […]
Chaganti J, Zeng G, Patil A, Lockart I, Dellalana M, Montagnese S, Brew B, Danta M Hepatology Background: Covert hepatic encephalopathy (CHE) is clinically underrecognized. Using MRI, we explored the relationship between functional connectivity as a marker of executive dysfunction and the blood-brain barrier permeability marker KTRANS in a cross-sectional cohort of covert HE (CHE), no […]
Montagnese S, Duarte-Rojo A Hepatology Full Text
Cajochen C, Montagnese S J Sleep Res While there is considerable enthusiasm for the translational and clinical applications of chronobiology, their actual implementation is not progressing as rapidly as might be expected. Here we discuss the possibility that this may relate to a combination of conceptual, methodological, evidentiary and training challenges. These are compounded by […]
Gachon F, Bugianesi E, Castelnuovo G, Oster H, Pendergast JS, Montagnese S NPJ Metab Health Dis Most aspects of physiology and behaviour fluctuate every 24 h in mammals. These circadian rhythms are orchestrated by an autonomous central clock located in the suprachiasmatic nuclei that coordinates the timing of cellular clocks in tissues throughout the body. […]
Zeng G, Krishnamurthy S, Staats Pires A, Guller A, Chaganti J, Tun N, Lockart I, Montagnese S, Brew B, Guillemin GJ, Danta M, Heng B Hepatol Commun Background: HE is a neuropsychiatric complication of liver disease characterized by systemic elevation in ammonia and proinflammatory cytokines. These neurotoxins cross the blood-brain barrier and cause neuroinflammation, which can […]
Roccarina D, Saltini D, Adotti V, Rosi M, Senzolo M, Nardelli S, Bianchini M, Biribin L, Caporali C, Margherita F, Ragozzino L, Guasconi T, Casari F, Gioia S, Campani C, Prampolini F, Ingravallo A, Gitto S, Aspite S, Arena U, Citone M, Gaggini M, Ridola L, Barbiero G, De Masi S, Riggio O, Merli M, […]
Domenie ED, Cusumano P, Montagnese S, Costa R Fly (Austin) The aim of the present study was to assess sleep timing in Drosophila melanogaster at different ages, within the setting of an enforced schedule of varying light-dark stimuli, simulating light exposure variations between four typical office working days and one free day spent outside by a human, for a total of […]
Biscontin A, Russo A, Marnetto D, Pagani L, Costa R, Montagnese S J Biol Rhythms The present study aimed to develop a TaqMan genotyping card for molecular chronotype assessment based on a predictive panel of 35 previously identified genetic variants. A reliable TaqMan assay was successfully developed for 33 out of the 35 chronotype-predictive variants. […]
Giusti G, Mangini C, Erminelli D, Domenie ED, Montagnese S Chronobiology International One of the main challenges in translating chronobiology research into clinical practice is represented by differences in how basic scientists and clinicians evaluate evidence. The workshop “Assessing Evidence in Translational Chronobiology,” which was held at the University of Surrey in June 2023, addressed […]
