Sleep and Rhythms Projects

Electrophysiological and hemodynamic mechanisms underlying load modulations in visuospatial working memory: A functional near-infrared spectroscopy (fNIRS) and electroencephalogram (EEG) study

Zarantonello L, Brigadoi S, Schiff S, Bisiacchi PS, Cutini S, Montagnese S, Amodio P Behav Neurosci The n-back task has been widely used to study working memory. Previous studies investigating the electrophysiological (electroencephalogram [EEG]) and hemodynamic correlates (functional near-infrared spectroscopy [fNIRS]) of the n-back task have been generally based on verbal stimuli and only investigated […]

Long-term effects of daylight saving time on driving fatigue

Orsini F, Domenie ED, Zarantonello L, Costa R, Montagnese S, Rossi R Heliyon The study of the relationship between Daylight Saving Time (DST) and road safety has yielded contrasting results, most likely in relation to the inability of crash-database approaches to unravel positive (ambient lighting-related) and negative (circadian/sleep-related) effects, and to significant geographical differences in […]

Proton pump inhibitor use and risk of hepatic encephalopathy: A multicentre study

Gairing SJ, Mangini C, Zarantonello L, Jonasson E, Dobbermann H, Sultanik P, Galle PR, Labenz J, Thabut D, Marquardt JU, Bloom PP, Lauridsen MM, Montagnese S, Labenz C JHEP Rep Background & aims: Data on the association between proton pump inhibitor (PPI) use and hepatic encephalopathy (HE) are conflicting, and data from multicentre studies are […]

The social and psychological impact of hepatic encephalopathy

Sørensen M, Lauridsen MM, Montagnese S Metab Brain Dis Hepatic encephalopathy (HE) is a brain dysfunction caused by liver insufficiency with symptoms ranging from slight cognitive changes detectable only by neuropsychiatric testing to coma. Up to 60% of patients with cirrhosis have mild forms of HE and 35% will at some point experience overt HE. […]

PHES scores have limited impact on the risk of overt HE in patients with minimal HE

Gairing SJ, Mangini C, Zarantonello L, Jonasson E, Danneberg S, Sultanik P, Galle PR, Gioia S, Labenz J, Lok AS, Marquardt JU, Lauridsen MM, Bloom PP, Thabut D, Nardelli S, Montagnese S, Labenz C Hepatol Commun Background: Minimal hepatic encephalopathy, defined by the portosystemic hepatic encephalopathy score (PHES), is associated with a higher risk of subsequent […]

Letter to the Editor: Health warning for humble writers, distracted reviewers and naive readers

Amodio P, Huang CH, Montagnese S Hepatology Full text

No Solid Reasons Not to Measure Ammonia

Amodio P, Montagnese S Clin Gastroenterol Hepatol Full Text

Overt Hepatic Encephalopathy: More Than Meets the Eye

Erminelli D, Mangini C, Zarantonello L, Angeli P, Montagnese S Am J Gastroenterol Introduction: We aimed to assess the reliability of a qualitative approach to overt hepatic encephalopathy (OHE) diagnosis compared with the semiquantitative, and recommended one. Methods: The above 2 methods were compared in 411 outpatients (71% males, 60 ± 10 years, model for end-stage liver […]

Personalising circadian hygiene educational initiatives aimed at university students-“He who has ears to hear, let him hear”

Giusti G, Domenie ED, Zarantonello L, Mangini C, Ferrari P, Costa R, Montagnese S J Sleep Res The aim of the present study was to characterise “early drop-outs” (n = 3185) out of a group of university students (n = 7766) engaged in an ongoing circadian education initiative, to evaluate its efficacy and direct its […]

Application of short-term analysis of skin temperature variability in prediction of survival in patients with cirrhosis

Abid NU, Lum Cheng In T, Bottaro M, Shen X, Hernaez Sanz I, Yoshida S, Formentin C, Montagnese S, Mani AR Front Netw Physiol Background: Liver cirrhosis is a complex disorder, involving several different organ systems and physiological network disruption. Various physiological markers have been developed for survival modelling in patients with cirrhosis. Reduction in heart […]