Category Archives: Sleep

Frontiers in Chronobiology: Endogenous Clocks at the Core of Signaling Pathways in Physiology

Costa R Frontiers in Physiology Chronobiology is a relatively young and fast evolving research field, which aims at understanding the origin, the mechanisms and the prerogatives of endogenous biological clocks. The Chronobiology section of Frontiers in Physiology provides an interdisciplinary forum for the publication of research covering all aspects of the field, including molecular clock […]

A pilot study of Golexanolone, a new GABA-A receptor modulating steroid antagonist, in patients with covert hepatic encephalopathy

Montagnese S, Lauridsen M, Vilstrup H, Zarantonello L, Lakner G, Fitilev S, Zupanets I, Kozlova I, Bunkova E, Tomasiewicz K, Berglund JE, Rorsman F, Hagström H, Kechagias S, Ocklind CE, Mauney J, Thunarf F, Mokhatarani M, Bäckström T, Doverskog M, Lins LE, Månsson M, Samuelson P, Nilsson D, Schalling M, Johansson M, Arlander E, Scharschmidt […]

Effect of Morning Light Glasses and Night Short-Wavelength Filter Glasses on Sleep-Wake Rhythmicity in Medical Inpatients

Formentin C, Carraro S, Turco M, Zarantonello L, Angeli P, Montagnese S Frontiers in physiology Sleep and circadian rhythm disorders are common amongst medical inpatients. They are caused by a mixture of factors, including noise, loss of habitual daily routines, and abnormal exposure to light, which tends to be insufficient in the day and too […]

Sleep, Circadian Rhythmicity and Response to Chronotherapy in University Students: Tips from Chronobiology Practicals

Montagnese S, Zarantonello L, Formentin C, Zancato C, Bonetto M B, Biscontin A, Cusumano P, Costa R (2021) Journal of Circadian Rhythms Chronobiology is not routinely taught to biology or medical students in most European countries. Here we present the results of the chronobiology practicals of a group of students of the University of Padova, with a […]

Gufi o allodole? Cosa sono e come funzionano gli orologi circadiani.

Costa R, Montagnese S L’orologio circadiano, che regola i ritmi sonno-veglia e altri aspetti della nostra fisiologia, si sincronizza con l’ambiente naturale che ci circonda, soprattutto per mezzo della luce del Sole. Tuttavia le nostre abitudini di vita, condizionate dall’orologio sociale, spesso confliggono con i ritmi dettati dall’orologio circadiano. Questo favorisce l’insorgenza di malattie, anche […]

The µMCTQ: An Ultra-Short Version of the Munich ChronoType Questionnaire.

Ghotbi N, Pilz LK, Winnebeck EC, Vetter C, Zerbini G, Lenssen D, Frighetto G, Salamanca M, Costa R, Montagnese S, Roenneberg T Journal of Biological Rhythms Individuals vary in how their circadian system synchronizes with the cyclic environment (zeitgeber). Assessing these differences in “phase of entrainment”-often referred to as chronotype-is an important procedure in laboratory […]

Predictive value of induced hyperammonaemia and neuropsychiatric profiling in relation to the occurrence of post-TIPS hepatic encephalopathy

Senzolo M, Zarantonello L, Formentin C, Orlando C, Beltrame F, Vuerich A, Angeli P, Burra P, Montagnese S Metabolic Brain Disease Hepatic encephalopathy (HE) occurs in 20–50% of patients after transjugular intrahepatic portosystemic shunt (TIPS) placement. Older age, HE history and severe liver failure have all been associated with post-TIPS HE but it remains difficult to […]

Morning Bright Light Treatment for Sleep-Wake Disturbances in Primary Biliary Cholangitis: A Pilot Study

Matteo Turco, Nora Cazzagon, Irene Franceschet, Chiara Formentin, Giovanni Frighetto, Francesca Giordani, Nicola Cellini, Gabriella Mazzotta, Rodolfo Costa, Benita Middleton, Debra J. Skene, Annarosa Floreani and Sara Montagnese Frontiers in Physiology Patients with Primary Biliary Cholangitis (PBC) exhibit delayed sleep-wake habits, disturbed night sleep and daytime sleepiness/fatigue. Such combination of symptoms is reminiscent of delayed […]