Zeng G, Krishnamurthy S, Staats Pires A, Guller A, Chaganti J, Tun N, Lockart I, Montagnese S, Brew B, Guillemin GJ, Danta M, Heng B Hepatol Commun Background: HE is a neuropsychiatric complication of liver disease characterized by systemic elevation in ammonia and proinflammatory cytokines. These neurotoxins cross the blood-brain barrier and cause neuroinflammation, which can […]
Roccarina D, Saltini D, Adotti V, Rosi M, Senzolo M, Nardelli S, Bianchini M, Biribin L, Caporali C, Margherita F, Ragozzino L, Guasconi T, Casari F, Gioia S, Campani C, Prampolini F, Ingravallo A, Gitto S, Aspite S, Arena U, Citone M, Gaggini M, Ridola L, Barbiero G, De Masi S, Riggio O, Merli M, […]
Gairing SJ, Mangini C, Zarantonello L, Jonasson E, Dobbermann H, Sultanik P, Galle PR, Labenz J, Thabut D, Marquardt JU, Bloom PP, Lauridsen MM, Montagnese S, Labenz C JHEP Rep Background & aims: Data on the association between proton pump inhibitor (PPI) use and hepatic encephalopathy (HE) are conflicting, and data from multicentre studies are […]
Sørensen M, Lauridsen MM, Montagnese S Metab Brain Dis Hepatic encephalopathy (HE) is a brain dysfunction caused by liver insufficiency with symptoms ranging from slight cognitive changes detectable only by neuropsychiatric testing to coma. Up to 60% of patients with cirrhosis have mild forms of HE and 35% will at some point experience overt HE. […]
Gairing SJ, Mangini C, Zarantonello L, Jonasson E, Danneberg S, Sultanik P, Galle PR, Gioia S, Labenz J, Lok AS, Marquardt JU, Lauridsen MM, Bloom PP, Thabut D, Nardelli S, Montagnese S, Labenz C Hepatol Commun Background: Minimal hepatic encephalopathy, defined by the portosystemic hepatic encephalopathy score (PHES), is associated with a higher risk of subsequent […]
Amodio P, Huang CH, Montagnese S Hepatology Full text
Amodio P, Montagnese S Clin Gastroenterol Hepatol Full Text
Erminelli D, Mangini C, Zarantonello L, Angeli P, Montagnese S Am J Gastroenterol Introduction: We aimed to assess the reliability of a qualitative approach to overt hepatic encephalopathy (OHE) diagnosis compared with the semiquantitative, and recommended one. Methods: The above 2 methods were compared in 411 outpatients (71% males, 60 ± 10 years, model for end-stage liver […]
Abid NU, Lum Cheng In T, Bottaro M, Shen X, Hernaez Sanz I, Yoshida S, Formentin C, Montagnese S, Mani AR Front Netw Physiol Background: Liver cirrhosis is a complex disorder, involving several different organ systems and physiological network disruption. Various physiological markers have been developed for survival modelling in patients with cirrhosis. Reduction in heart […]
Friis KH, Thomsen KL, Laleman W, Montagnese S, Vilstrup H, Lauridsen MM J Clin Med Transjugular intrahepatic portosystemic shunt (TIPS) is an established treatment for portal hypertension and its’ complications in liver cirrhosis, yet the development of hepatic encephalopathy (HE) remains a significant concern. This review covers the reported incidence, risk factors, and management strategies […]
