Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia
Marini S, Santangeli O, Saarelainen P, Middleton B, Chowdhury N, Skene DJ, Costa R,Porkka-Heiskanen T, Montagnese S Frontiers in Physiology (section Integrative Physiology) Patients with liver cirrhosis can develop hyperammonemia and hepatic encephalopathy (HE), accompanied by pronounced daytime sleepiness. Previous studies with healthy volunteers show that experimental increase in blood ammonium levels increases sleepiness and slows […]
Diurnal preference, mood and the response to morning light in relation to polymorphisms in the human clock gene PER3
Turco M, Biscontin A, Corrias M, Caccin L, Bano M, Chiaromanni F, Salamanca M, Mattei D, Salvoro C, Mazzotta G, De Pittà C, Middleton M, Skene D, Montagnese S, Costa R. Scientific reports PER3 gene polymorphisms have been associated with differences in human sleep-wake phenotypes, and sensitivity to light. The aims of this study were […]
Abnormalities in the 24-hour Rhythm of Skin Temperature in Cirrhosis: Sleep-Wake and General Clinical Implications
Garrido M, Saccardo D, De Rui M, Vettore E, Verardo A, Carraro P, Di Vitofrancesco N, Mani AR, Angeli P, Bolognesi M, Montagnese S. Liver International BACKGROUND & AIMS: Sleep preparation/onset are associated with peripheral vasodilatation and a decrease in body temperature. The hyperdynamic syndrome exhibited by patients with cirrhosis may impinge on sleep preparation, […]
Expected accuracy of proximal and distal temperature estimated by wireless sensors, in relation to their number and position on the skin
Longato E, Garrido M, Saccardo D, Montesinos Guevara C, Mani A, Bolognesi M, Amodio P, Facchinetti A, Sparacino G, Montagnese S. PlosOne A popular method to estimate proximal/distal temperature (TPROX and TDIST) consists in calculating a weighted average of nine wireless sensors placed on pre-defined skin locations. Specifically, TPROX is derived from five sensors placed […]
The animal naming test: An easy tool for the assessment of hepatic encephalopathy.
Campagna F, Montagnese S, Ridola L, Senzolo M, Schiff S, De Rui M, Pasquale C, Nardelli S, Pentassuglio I, Merkel C, Angeli P, Riggio O, Amodio P. Hepatology. 2017 Screening for hepatic encephalopathy (HE) that does not cause obvious disorientation or asterixis (minimal HE [MHE]/grade 1 HE) is important. We examined if the animal naming test (ANT1 ) (maximum number of animals listed […]