Mangini C, Montagnese S J Clin Med Hepatic encephalopathy (HE) is a common complication of advanced liver disease which has profound implications in terms of the patients’ ability to fulfil their family and social roles, to drive and to provide for themselves. Recurrent and persistent HE is still a serious management challenge, translating into a […]
Brischigliaro M, Frigo E, Corrà S, De Pittà C, Szabò I, Zeviani M, Costa R Journal of Molecular Medicine Mutations in BCS1L are the most frequent cause of human mitochondrial disease linked to complex III deficiency. Different forms of BCS1L-related diseases and more than 20 pathogenic alleles have been reported to date. Clinical symptoms are highly heterogenous, and […]
Ponziani FR, Aghemo A, Cabibbo G, Masarone M, Montagnese S, Petta S, Russo FP, Lai Q; AISF COVID-19 survey group Liver International Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has severely limited the clinical activity of most hospitals around the world. A previous survey of the Italian Association for the Study of the Liver (AISF) […]
Garcia-Pagan JC, Francoz C, Montagnese S, Senzolo M, Mookerjee RP Journal of Hepatology Along with a growing understanding of the pathophysiology of cirrhosis and its complications, new therapies and management strategies have emerged in recent years. Many of these advances have helped inform the current EASL clinical practice guidelines1 on the management of some of […]
Costa R Frontiers in Physiology Chronobiology is a relatively young and fast evolving research field, which aims at understanding the origin, the mechanisms and the prerogatives of endogenous biological clocks. The Chronobiology section of Frontiers in Physiology provides an interdisciplinary forum for the publication of research covering all aspects of the field, including molecular clock […]
Russo F P, Piano S, Bruno R, Burra P, Puoti M, Masarone M, Montagnese S, Ponziani F R, Petta S, Aghemo A, Italian Association for the Study of the Liver Digestive and Liver Disease The vaccination campaign against Sars-CoV-2 commenced in Italy at the end of December 2020. The first ones to receive the immunization […]
Montagnese S, Lauridsen M, Vilstrup H, Zarantonello L, Lakner G, Fitilev S, Zupanets I, Kozlova I, Bunkova E, Tomasiewicz K, Berglund JE, Rorsman F, Hagström H, Kechagias S, Ocklind CE, Mauney J, Thunarf F, Mokhatarani M, Bäckström T, Doverskog M, Lins LE, Månsson M, Samuelson P, Nilsson D, Schalling M, Johansson M, Arlander E, Scharschmidt […]
Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I Nat Commun. Mitochondrial diseases impair oxidative phosphorylation and ATP production, while effective treatment is still lacking. Defective complex III is associated with a highly variable […]
Haspel J, Kim M, Zee P, Schwarzmeier T, Montagnese S, Panda S, Albani A, Merrow M Journal of Biological Rhythms We currently find ourselves in the midst of a global coronavirus disease 2019 (COVID-19) pandemic, caused by the highly infectious novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss aspects of SARS-CoV-2 […]
Montagnese S, Bajaj JS Drugs Hepatic encephalopathy (HE) has a major impact on health-related quality of life (HRQOL) in patients, which has clinical and psychosocial consequences. HRQOL in cirrhosis has been measured by generic and liver-specific instruments, with most studies indicating a negative impact of HE. HRQOL abnormalities span daily functioning, sleep–wake cycle changes, and […]
