Montagnese S, Gómez MR, Larsen FS, Shawcross D, Thabut D, Vilstrup HA V, Weissenborn K, Rautou PE, Corresponding author: European Association for the Study of the Liver (EASL) Journal of Hepatology The EASL Clinical Practice Guidelines (CPGs) on the management of hepatic encephalopathy (HE) present evidence-based answers to a set of relevant questions (where possible, […]
Mangini C, Zarantonello L, Formentin C, Giusti G, Angeli P, Montagnese S Digestive and Liver Disease Objectives Few data on hepatic encephalopathy (HE) over time are available, thus our aim was to study its evolution in patients with varying degree of HE on first assessment. Methods Eighty-six patients with cirrhosis (age = 58 ± 11 […]
Brischigliaro M, Badocco D, Costa R, Viscomi C, Zeviani M, Pastore P, Fernández-Vizarra E Front Cell Dev Biol The redox activity of cytochrome c oxidase (COX), the terminal oxidase of the mitochondrial respiratory chain (MRC), depends on the incorporation of iron and copper into its catalytic centers. Many mitochondrial proteins have specific roles for the synthesis and […]
Biscontin A, Zarantonello L, Russo A, Costa R, Montagnese R J Biol Rhythms The aim of the present study was to develop a Polygenic Score-based model for molecular chronotype assessment. Questionnaire-based phenotypical chronotype assessment was used as a reference. In total, 54 extremely morning/morning (MM/M; 35 females, 39.7 ± 3.8 years) and 44 extremely evening/evening […]
Montagnese S, Zarantonello L, Formentin C, Giusti G, Mangini C, Isherwood CM, Ferrari P, Paoli A, Mapelli D, Rizzuto R, Toppo S, Skene DJ, Vettor R, Costa R Front Neurosci The aims of the present study were to obtain sleep quality and sleep timing information in a group of university students and to evaluate the […]
Marnetto D, Pankratov V, Mondal M, Montinaro F, Pärna K, Vallini L, Molinaro L, Saag L, Loog L, Montagnese S, Costa R, Estonian Biobank Research Team, Metspalu M, Eriksson A, Pagani L Current Biology The contemporary European genetic makeup formed in the last 8,000 years when local Western Hunter-Gatherers (WHGs) mixed with incoming Anatolian Neolithic […]
Costa R, Kyriacou C Front Physiol Circadian rhythms are ubiquitous and are observed in nearly all organisms that have been studied which inhabit our planet. These include animals, plants, fungi as well as some bacteria. These endogenous clocks will tick along nicely with an approximately 24 h period in constant conditions because they are generated […]
Mangini C, Montagnese S J Clin Med Hepatic encephalopathy (HE) is a common complication of advanced liver disease which has profound implications in terms of the patients’ ability to fulfil their family and social roles, to drive and to provide for themselves. Recurrent and persistent HE is still a serious management challenge, translating into a […]
Brischigliaro M, Frigo E, Corrà S, De Pittà C, Szabò I, Zeviani M, Costa R Journal of Molecular Medicine Mutations in BCS1L are the most frequent cause of human mitochondrial disease linked to complex III deficiency. Different forms of BCS1L-related diseases and more than 20 pathogenic alleles have been reported to date. Clinical symptoms are highly heterogenous, and […]
Ponziani FR, Aghemo A, Cabibbo G, Masarone M, Montagnese S, Petta S, Russo FP, Lai Q; AISF COVID-19 survey group Liver International Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has severely limited the clinical activity of most hospitals around the world. A previous survey of the Italian Association for the Study of the Liver (AISF) […]
