SleepRhythm – Page 10 – Sleep & Rhythm

Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia

Marini S, Santangeli O, Saarelainen P, Middleton B, Chowdhury N, Skene DJ, Costa R,Porkka-Heiskanen T, Montagnese S Frontiers in Physiology (section Integrative Physiology) Patients with liver cirrhosis can develop hyperammonemia and hepatic encephalopathy (HE), accompanied by pronounced daytime sleepiness. Previous studies with healthy volunteers show that experimental increase in blood ammonium levels increases sleepiness and slows […]

Diurnal preference, mood and the response to morning light in relation to polymorphisms in the human clock gene PER3

Turco M, Biscontin A, Corrias M, Caccin L, Bano M, Chiaromanni F, Salamanca M, Mattei D, Salvoro C, Mazzotta G, De Pittà C, Middleton M, Skene D, Montagnese S, Costa R. Scientific reports PER3 gene polymorphisms have been associated with differences in human sleep-wake phenotypes, and sensitivity to light. The aims of this study were […]

Abnormalities in the 24-hour Rhythm of Skin Temperature in Cirrhosis: Sleep-Wake and General Clinical Implications

Garrido M, Saccardo D, De Rui M, Vettore E, Verardo A, Carraro P, Di Vitofrancesco N, Mani AR, Angeli P, Bolognesi M, Montagnese S. Liver International BACKGROUND & AIMS: Sleep preparation/onset are associated with peripheral vasodilatation and a decrease in body temperature. The hyperdynamic syndrome exhibited by patients with cirrhosis may impinge on sleep preparation, […]

Expected accuracy of proximal and distal temperature estimated by wireless sensors, in relation to their number and position on the skin

Longato E, Garrido M, Saccardo D, Montesinos Guevara C, Mani A, Bolognesi M, Amodio P, Facchinetti A, Sparacino G, Montagnese S. PlosOne A popular method to estimate proximal/distal temperature (TPROX and TDIST) consists in calculating a weighted average of nine wireless sensors placed on pre-defined skin locations. Specifically, TPROX is derived from five sensors placed […]

The animal naming test: An easy tool for the assessment of hepatic encephalopathy.

Campagna F, Montagnese S, Ridola L, Senzolo M, Schiff S, De Rui M, Pasquale C, Nardelli S, Pentassuglio I, Merkel C, Angeli P, Riggio O, Amodio P. Hepatology. 2017 Screening for hepatic encephalopathy (HE) that does not cause obvious disorientation or asterixis (minimal HE [MHE]/grade 1 HE) is important. We examined if the animal naming test (ANT1 ) (maximum number of animals listed […]

Neuropsychiatric performance in patients with cirrhosis: Who is “normal”?

Montagnese S, De Rui M, Angeli P, Amodio P. Journal of Hepatology 2017 In patients with cirrhosis a normal neuropsychiatric performance has been traditionally defined by the absence of any degree of hepatic encephalopathy and/or the absence of psychometric or neurophysiological abnormalities, compared with data from the healthy population. As the understanding and management of end-stage liver disease continues to change, it is our impression […]

Identifying pathways modulating sleep duration: from genomics to transcriptomics

Allebrandt K, Teder-Laving M, Cusumano P, Frishman G, Levandovski R, Ruepp A, Hidalgo M, Costa R, Metspalu A, Roenneberg T, de Pittà C. Scientific Reports Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for […]

Cognitive reserve is a resilience factor for cognitive dysfunction in hepatic encephalopathy

Amodio P, Montagnese S, Spinelli G, Schiff S, Mapelli D. Metababolic Brain Disease 2017 Cognitive Reserve (CR) modulates symptoms of brain disease. The aim of this study was: to evaluate the effect of CR on cognition in cirrhosis and on the mismatch between cognitive and neurophysiologic assessment of hepatic encephalopathy (HE). Eighty-two outpatient patients with cirrhosis without overt HE were studied [73% […]

An educational tool for the prophylaxis of hepatic encephalopathy.

Garrido M, Turco M, Formentin C, Corrias M, De Rui M, Montagnese S, Amodio P. BMJ Open Gastroenterology 2017 BACKGROUND: Providing structured information for the understanding of hepatic encephalopathy (HE) might be relevant to the prevention and management of the syndrome. The aim of our study was to design a brief, structured educational intervention and […]

KrillDB: A de novo transcriptome database for the Antarctic krill (Euphausia superba).

Sales G, Deagle BE, Calura E, Martini P, Biscontin A, De Pittà C, Kawaguchi S, Romualdi C, Meyer B, Costa R, Jarman S. PLoS One Abstract Antarctic krill (Euphausia superba) is a key species in the Southern Ocean with an estimated biomass between 100 and 500 million tonnes. Changes in krill population viability would have […]

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