All posts by SleepRhythm

Cognitive reserve is a resilience factor for cognitive dysfunction in hepatic encephalopathy

Amodio P, Montagnese S, Spinelli G, Schiff S, Mapelli D. Metababolic Brain Disease  2017 Cognitive Reserve (CR) modulates symptoms of brain disease. The aim of this study was: to evaluate the effect of CR on cognition in cirrhosis and on the mismatch between cognitive and neurophysiologic assessment of hepatic encephalopathy (HE). Eighty-two outpatient patients with cirrhosis without overt HE were studied [73% […]

  • 18 March 2017
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An educational tool for the prophylaxis of hepatic encephalopathy.

Garrido M, Turco M, Formentin C, Corrias M, De Rui M, Montagnese S, Amodio P. BMJ Open Gastroenterology  2017 BACKGROUND: Providing structured information for the understanding of hepatic encephalopathy (HE) might be relevant to the prevention and management of the syndrome. The aim of our study was to design a brief, structured educational intervention and […]

  • 12 February 2017
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KrillDB: A de novo transcriptome database for the Antarctic krill (Euphausia superba).

Sales G, Deagle BE, Calura E, Martini P, Biscontin A, De Pittà C, Kawaguchi S, Romualdi C, Meyer B, Costa R, Jarman S. PLoS One Abstract Antarctic krill (Euphausia superba) is a key species in the Southern Ocean with an estimated biomass between 100 and 500 million tonnes. Changes in krill population viability would have […]

  • 1 February 2017
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Sleep-Wake Profile in Dementia with Lewy Bodies, Alzheimer’s Disease, and Normal Aging

Cagnin A, Fragiacomo F, Camporese G, Turco M, Bussè C, Ermani M, Montagnese S. Journal of  Alzheimers Disease  BACKGROUND: Alterations of the sleep-wake cycle are common features of neurodegenerative dementia. OBJECTIVES: To study differences in sleep-wake profiles in dementia with Lewy bodies (DLB), Alzheimer’s disease (AD), and healthy controls. METHODS: 30 DLB and 32 AD patients, […]

  • 1 January 2017
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Vigilance and wake EEG architecture in simulated hyperammonaemia: a pilot study on the effects of L-Ornithine-L-Aspartate (LOLA) and caffeine

Garrido M, Skorucak J, Raduazzo D, Turco M, Spinelli G, Angeli P, Amodio P, Achermann P, Montagnese S. Metabolic Brain Disease  Hyperammonaemia/mild hepatic encephalopathy (HE) can be simulated by the oral administration of a so-called amino acid challenge (AAC). This study sought to assess the effects of the AAC alone and in combination with either […]

  • 1 August 2016
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A low-cost, user-friendly electroencephalographic recording system for the assessment of hepatic encephalopathy.

Schiff S, Casa M, Di Caro V, Aprile D, Spinelli G, De Rui M, Angeli P, Amodio P, Montagnese S. Hepatology. 2016 Electroencephalography (EEG) is useful to objectively diagnose/grade hepatic encephalopathy (HE) across its spectrum of severity. However, it requires expensive equipment, and hepatogastroenterologists are generally unfamiliar with its acquisition/interpretation. Recent technological advances have led to the development […]

  • 18 January 2016
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Drosophila circadian rhythms in seminatural environments: Summer afternoon component is not an artifact and requires TrpA1 channels.

Green EW, O’Callaghan EK, Hansen CN, Bastianello S, Bhutani S, Vanin S, Armstrong JD, Costa R, Kyriacou CP. Proceeding of the National Academy of Sciences Abstract Under standard laboratory conditions of rectangular light/dark cycles and constant warm temperature, Drosophila melanogaster show bursts of morning (M) and evening (E) locomotor activity and a “siesta” in the […]

  • 1 July 2015
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Period and timeless mRNA Splicing Profiles under Natural Conditions in Drosophila melanogaster.

Montelli S, Mazzotta G, Vanin S, Caccin L, Corrà S, De Pittà C, Boothroyd C, Green EW, Kyriacou CP, Costa . Journal of biological rhythms Abstract Previous analysis of Drosophila circadian behavior under natural conditions has revealed a number of novel and unexpected features. Here we focus on the oscillations of per and tim mRNAs […]

  • 1 June 2015
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Assessment of 6-sulfatoxymelatonin rhythms and melatonin response to light in disease states: lessons from cirrhosis.

Montagnese S, Middleton B, Corrias M, Mani AR, Skene DJ, Morgan MY. Chronobiology International Abstract Circadian rhythmicity and non-visual sensitivity to light can be assessed, in healthy subjects, by measuring the rhythm of the urinary melatonin metabolite 6-sulphatoxymelatonin (aMT6s) and by determining the response of plasma melatonin to nocturnal retinal light exposure, respectively. However, the […]

  • 1 March 2015
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Nucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clock.

Bee L, Marini S, Pontarin G, Ferraro P, Costa R, Albrecht U, Celotti L. Nucleic Acids Research Abstract The efficiency of Nucleotide Excision Repair (NER)process is crucial for maintaining genomic integrity because in many organisms, including humans, it represents the only system able to repair a wide range of DNA damage. The aim of the […]

  • 1 February 2015
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