Acute hyperammonaemia induces a sustained decrease in vigilance, which is modulated by caffeine.
Casula EP, Bisiacchi PS, Corrias M, Schiff S, Merkel C, Amodio P, Montagnese S. Metabolic Brain Disease Abstract Hyperammonaemia is observed after prolonged, intense exercise, or in patients with hepatic failure. In the latter, it is associated with a set of neurological and psychiatric abnormalities termed hepatic encephalopathy. THE AIMS OF OUR STUDY WERE: 1. […]
Sleep and circadian rhythms in hospitalized patients with decompensated cirrhosis: effect of light therapy.
De Rui M, Middleton B, Sticca A, Gatta A, Amodio P, Skene DJ, Montagnese S. Neurochemistry Research Abstract Patients with liver cirrhosis often exhibit sleep-wake abnormalities, which are, at least to some extent, circadian in origin. A relatively novel non-pharmacological approach to circadian disruption is appropriately timed bright light therapy. The aims of this pilot […]
The influence of environmental factors on sleep quality in hospitalized medical patients.
Turco M, Corrias M, Chiaromanni F, Bano M, Salamanca M, Caccin L, Merkel C, Amodio P, Romualdi C, De Pittà C, Costa R, Montagnese S. Chronobiology International The assessment of diurnal preference, or the preferred timing of sleep and activity, is generally based on comprehensive questionnaires such as the Horne-Östberg (HÖ). The aim of the […]
The influence of environmental factors on sleep quality in hospitalized medical patients
Bano M, Chiaromanni F, Corrias M, Turco M, De Rui , Amodio P, Merkel C, Gatta A, Mazzotta G, Costa R, Montagnese S. Frontiers in Neurology INTRODUCTION: Sleep-wake disturbances are common in hospitalized patients but few studies have assessed them systematically. The aim of the present study was to assess sleep quality in a group […]
Fly cryptochrome and the visual system.
Mazzotta G, Rossi A, Leonardi E, Mason M, Bertolucci C, Caccin L, Spolaore B, Martin AJ, Schlichting M, Grebler R, Helfrich-Förster C, Mammi S, Costa R, Tosatto SC. Proceeding of the National Academy of Sciences Abstract Cryptochromes are flavoproteins, structurally and evolutionarily related to photolyases, that are involved in the development, magnetoreception, and temporal organization […]