Publications

The RNA helicase BELLE is involved in circadian rhythmicity and in transposons regulation in Drosophila melanogaster

Paola Cusumano, Milena Damulewicz, Elena Carbognin, Laura Caccin, Antonietta Puricella, Valeria Specchia, Maria Pia Bozzetti, Rodolfo Costa, Gabriella M. Mazzotta Frontiers in Physiology Circadian clocks control and synchronize biological rhythms of several behavioral and physiological phenomena in most, if not all, organisms. Rhythm generation relies on molecular auto-regulatory oscillations of interlocked transcriptional-translational feedback loops. Rhythmic clock-gene […]

The Psychomotor Vigilance Task: Role in the Diagnosis of Hepatic Encephalopathy and Relationship with Driving Ability.

Formentin Chiara, De Rui Michele, Zoncapè Mirco, Ceccato Silvia, Zarantonello Lisa, Senzolo Marco, Burra Patrizia, Angeli Paolo, Amodio Piero, Montagnese Sara Journal of Hepatology BACKGROUND & AIMS: Hepatic Encephalopathy (HE) is a syndrome of decreased vigilance, and has been associated with impaired driving ability. The aim of this study was to evaluate the Psychomotor Vigilance […]

Hepatic encephalopathy 2018: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)

Sara Montagnese,Francesco Paolo Russo, Piero Amodio, Patrizia Burra, Antonio Gasbarrini, Carmela Loguercio, Giulio Marchesini, Manuela Merli, Francesca Romana Ponziani, Oliviero Riggio, Carmelo Scarpignato Digestive and Liver Disease Hepatic encephalopathy (HE) is a common, worrisome and sometimes difficult to manage complication of end-stage liver disease. HE is often recurrent, requiring multiple hospital admissions. It can have […]

Morning Bright Light Treatment for Sleep-Wake Disturbances in Primary Biliary Cholangitis: A Pilot Study

Matteo Turco, Nora Cazzagon, Irene Franceschet, Chiara Formentin, Giovanni Frighetto, Francesca Giordani, Nicola Cellini, Gabriella Mazzotta, Rodolfo Costa, Benita Middleton, Debra J. Skene, Annarosa Floreani and Sara Montagnese Frontiers in Physiology Patients with Primary Biliary Cholangitis (PBC) exhibit delayed sleep-wake habits, disturbed night sleep and daytime sleepiness/fatigue. Such combination of symptoms is reminiscent of delayed […]

Cryptochrome Is a Regulator of Synaptic Plasticity in the Visual System of Drosophila melanogaster

Damulewicz M, Mazzotta GM, Sartori E, Rosato E, Costa R, Pyza EM Frontiers in Molecular Neuroscience, 2017 Drosophila CRYPTOCHROME (CRY) is a blue light sensitive protein with a key role in circadian photoreception. A main feature of CRY is that light promotes an interaction with the circadian protein TIMELESS (TIM) resulting in their ubiquitination and degradation, a […]